Ada Undieh (email) is a PhD candidate in Chemical Engineering in the Fuller Research Group at Stanford University. She is interested in engineering approaches that address "black boxes" in development and disease; particularly, how chemical and mechanical cues are integrated across length scales to drive coordinated cell behavior. She received her B.S.E. in Chemical and Biological Engineering at Princeton University and is currently supported by the Stanford Chemistry, Engineering, and Medicine for Human Health (ChEM-H) at the Chemical-Biological Interface (CBI) Training Program, the Stanford Enhancing Diversity in Graduate Education (EDGE) Fellowship, and the Stanford Graduate Fellowship (SGF).
Talk details: Live cell rheometer: integrated imaging and mechanical measurement of living cell multilayers and tissues
Changes in the mechanical properties of cells and in friction at cell interfaces are implicated in normal development and in the pathology of many major diseases, including atherosclerosis, dry eye disease, and cancer. In this work, we describe the application of a novel live cell rheometer to study tissue response to shear in two in vitro models.